Área de Genómica
Juan Pereda, Rafael Espinosa, Blanca García-Solís, Teresa Guerra-Galán, Ana Van-Den-Rym, Meltem Ece Kars, Rocío Mena, Victor Galán, Ana de Andrés-Martín, Carlos Rodríguez-Gallego, Alberto López-Lera, Fernando Corvillo, Antonio Pérez-Martínez, Eduardo López-Collazo, Silvia Sánchez-Ramón, Rubén Martínez-Barricarte, Lluis Quintana-Murci, José Miguel Lorenzo-Salazar, Yuval Itan, Carlos Flores, Rebeca Pérez-de-Diego. IEIVariantFilter: a bioinformatics tool to speed up genetic diagnosis of inborn errors of immunity patients, NAR Genomics and Bioinformatics, 7(2), 2025, lqaf069. doi:https://doi.org/10.1093/nargab/lqaf069
Rodríguez-Pérez, H., Ciuffreda, L., Hernández-Beeftink, T., Guillen-Guio, B., Domínguez, D., Corrales, A., Espinosa, E., Alcoba-Florez, J., Lorenzo-Salazar, J. M., González-Montelongo, R., Villar, J., & Flores, C. (2025). Tracheal Aspirate Metagenomics Reveals Association of Antibiotic Resistance with Nonpulmonary Sepsis Mortality. American journal of respiratory cell and molecular biology, 72(2), 219–222. doi: https://doi.org/10.1165/rcmb.2024-0192LE
Alonso-González, A., Véliz-Flores, I., Tosco-Herrera, E., González-Barbuzano, S., Mendoza-Alvarez, A., Galván-Fernández, H., Sastre, L., Fernández-Varas, B., Corrales, A., Rubio-Rodríguez, L. A., Jáspez, D., Lorenzo-Salazar, J. M., Molina-Molina, M., Rodríguez-de-Castro, F., González-Montelongo, R., Flores, C. (2025). A tiered strategy to identify relevant genetic variants in familial pulmonary fibrosis: a proof of concept for the clinical practice. European journal of human genetics : EJHG, 10.1038/s41431-024-01772-y. Advance online publication. doi: https://doi.org/10.1038/s41431-024-01772-y
Justin Wagner, Nathan D. Olson, Jennifer McDaniel, Lindsay Harris, Brendan J. Pinto, David Jáspez, Adrián Muñoz-Barrera, Luis A. Rubio-Rodríguez, José M. Lorenzo-Salazar, Carlos Flores, Sayed Mohammad Ebrahim Sahraeian, Giuseppe Narzisi, Marta Byrska-Bishop, Uday S. Evani, Chunlin Xiao, Juniper A. Lake, Peter Fontana, Craig Greenberg, Donald Freed, Mohammed Faizal Eeman Mootor, Paul C. Boutros, Lisa Murray, Kishwar Shafin, Andrew Carroll, Fritz J. Sedlazeck, Melissa Wilson, Justin M. Zook (2024). Small variant benchmark from a complete assembly of X and Y chromosomes. Nat Commun 16, 497 (2025). doi: https://doi.org/10.1038/s41467-024-55710-z
Cabrera-Alarcon JL, Cruz R, Rosa-Moreno M, Latorre-Pellicer A, de Almeida SD; Scourge Cohort Group; Riancho JA, Rojas-Martinez A, Flores C, Lapunzina P, Sánchez-Cabo F, Carracedo Á, Enriquez JA (2025). Shaping current European mitochondrial haplogroup frequency in response to infection: the case of SARS-CoV-2 severity. Commun Biol.2025 Jan 9;8(1):33. doi: https://doi.org/10.1038/s42003-024-07314-y
Mendoza-Alvarez A., Martinez-Tadeo J.A., Perez-Rodríguez E., Barrios-Recio J., García-Robaina J.C., Corrales A., Marcelino-Rodríguez I., Lorenzo-Salazar J.M., González-Montelongo R., Flores C., Callero A. Whole Exome Sequencing in Drug-Induced Angioedema Caused by Angiotensin-Converting Enzyme Inhibitors: A Pilot Study in Five Patients. J. Clin. Med. 2025, 14(5), 1659. doi: https://doi.org/10.3390/jcm14051659
Serra-Llovich A., Cullell N., Maroñas O., Herrero M.J., Cruz R., Almoguera B., Ayuso C., López-Rodríguez R., Domínguez-Garrido E., Ortiz-Lopez R., Barreda-Sánchez M., Corton M., Dalmau D., Calbo E., Boix-Palop L., Dietl B., Sangil A., Gil-Rodriguez A., Guillén-Navarro E., Mancebo E., Lira-Albarán S., Minguez P., Paz-Artal E., Olivera G.G., Recarey-Rama S., Sendra L., Zucchet E.G., López de Heredia M., Flores C., Riancho J.A., Rojas-Martinez A., Lapunzina P., Carracedo A., Arranz M.J., and SCOURGE COHORT GROUP. Pharmacogenomic Study of SARS-CoV-2 Treatments: Identifying Polymorphisms Associated with Treatment Response in COVID-19 Patients. Biomedicines 2025, 13(3), 553. dopi: https://doi.org/10.3390/biomedicines13030553
Al Qureshah F, Le Pen J, Weerd NA, Moncada-Velez M, Materna M, Lin DC, Milisavljevic B, Vianna F, Bizien L, Lorenzo L, Lecuit M, Pommier JD, Keles S, Ozcelik T, Pedraza-Sanchez S, de Prost N, El Zein L, Hammoud H, Ng LFP, Halwani R, Sharif-Askari NS, Lau YL, Tam AR, Singh N, Bhattad S, Berkun Y, Chantratita W, Aguilar-López R, Shahrooei M, COVID-19 HGE Consortium*, SEAe Consortium, Abel L, Bastard P, Jouanguy E, Béziat V, Zhang P, Rice CM, Cobat A, Zhang SY, Hertzog PJ, Casanova JL, Zhang Q. (2025) A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity. Journal of Experimental Medicine 222: e20241413. Flores C es miembro del grupo*. doi: https://doi.org/10.1084/jem.20241413
Zhang W, Nguyen-Hoang N, Rivrud SCS, Zandbergen AF, Yan Y, Cox EGM, Suarez-Pajes E, Chong AY, Mentzer AJ, Flores C, Lunter G, Keus F, Snieder H. Genetic association studies in critically ill patients: A systematic review. eBioMedicine 2025, 114: 105678. doi: https://doi.org/10.1016/j.ebiom.2025.105678
Aitana Alonso-González, David Jáspez, José M Lorenzo-Salazar, Shwu-Fan Ma, Emma Strickland, Josyf Mychaleckyj, John S Kim, Yong Huang, Ayodeji Adegunsoye, Justin M Oldham, Iain Stewart, Philip L Molyneaux, Toby M Maher, Louise V Wain, Richard J Allen, R Gisli Jenkins, Jonathan A Kropski, Brian Yaspan, Timothy S Blackwell, David Zhang, Christine Kim Garcia, Fernando J Martinez, Imre Noth, Carlos Flores. Rare variants and survival of patients with idiopathic pulmonary fibrosis: analysis of a multicentre, observational cohort study with independent validation. The Lancet Respiratory Medicine 2025. doi: https://doi.org/10.1016/S2213-2600(25)00045-1
Área de Medioamiente
Asensio-Ramos M., Pardo Cofrades A., Burton M., La Spina A., Allard P., Barrancos J., Hayer C., Esse B., D’Auria L., Hernández P.A., Padrón E., Melián G. V. and Pérez N. M. (2025). Insights into magma dynamics from daily OP-FTIR gas compositions throughout the 2021 Tajogaite eruption, La Palma, Canary Islands. Chemical Geology, 676, 122605. DOI: 10.1016/j.chemgeo.2024.122605
Longpré M. A., Tramontano S., Pankhurst M.J., Roman D. C., Reiss M. C., Cortese F., James M. R., Spina L., Rodríguez F., Coldwell B., Martín-Lorenzo A., Barbee O., D’Auria L., Chamberlain K. J. and Scarrow J. (2025). Shifting melt composition linked to volcanic tremor at Cumbre Vieja volcano. Nature Geoscience. https://doi.org/10.1038/s41561-024-01623-x
Conde-Díaz A., Rodríguez-Ramos R., Asensio-Ramos M., Socas-Rodríguez B., Herrera-Herrera A. V. (2025). Analysis of organic contaminants in food: other organic compounds. In Socas-Rodríguez B., Herrera-Herrera A. V., Gil-Ramírez A., Rostagno M. A. (Eds.), Sustainable Analytical Techniques in Food Science (pp. 377-432). Elsevier. https://doi.org/10.1016/B978-0-443-13959-8.00012-0